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Metoclopramide is an effective migraine treatment for adults–as few as four patients need to be treated to enable one to achieve significant pain reduction. But other antiemetics may have more effect on pain and migraine-related nausea, according to Ian Colman, a postgraduate student at the University of Cambridge (England), and his colleagues.
Their metaanalysis included five studies of metoclopramide vs. placebo (263 adults); three studies of metoclopra…